Could Psychedelic Drugs Treat Depression and Anxiety?

Scientists in the U.S have demonstrated how psychedelic drugs such as 2,5-dimethoxy-4-iodoamphetamine ( DOI), 3,4-methylenedioxymethamphetamine ( MDMA), N , N -dimethyltryptamine (DMT), and lysergic acid diethylamide ( LSD), cause structural and functional changes in brain cells that could feasibly be harnessed to help treat depression and related disorders. Depression is known to cause the atrophy of neurons in the prefrontal cortex (PFC) in the brain, and  in vitro and in vivo studies by researchers at the University of California, Davis, have found that different classes of psychedelic drugs increase the numbers of neuronal branches, or dendrites, as well as the density of dendritic spines and synapses in cortical neurons. Some psychedelics tested, including LSD, demonstrated structural effects that were even more potent than those of the anesthetic ketamine, which over the last two decades has been the subject of intense research as a potentially fast-acting antidepressant for people ...