From killers to strategists: CAR T cells enter their multifunctional era
A review of 1,801 registered CAR T clinical trials shows that multifunctional designs now account for 533 trials and 33% of new CAR T products
Category: Health
Single-cell sequencing reveals why some CAR-T therapies succeed while others fail
Single-cell RNA sequencing is giving researchers a clearer view of why some CAR-T cells persist, expand, kill tumors effectively, or become exhausted. The review synthesizes
Metabolic rewiring could help CAR-T cells fight solid tumors
This review explains how glucose scarcity, lipid disruption, amino acid deprivation, and toxic metabolites weaken CAR-T cells inside solid tumors. It highlights metabolic reprogramming as
‘Amazing’ moment for communities given right to buy for the first time
Ministers say the new law in England gives power to local people who want to help others.
How multi-omics is changing what scientists can see in the human immune system
Human systems immunology is using multi-omics, single-cell tools, spatial technologies, and AI to decode immune responses across real-world human cohorts. The review highlights major opportunities
A Tale of Two Books: We Want Them Infected & In COVID’s Wake
I am not afraid to defend my book by discussing the real-world job performance of the MAHA/MAGA doctors featured in it. What about the authors
Women can wait years for an endometriosis diagnosis. New tech could change that
A new scan technique could spot areas of endometriosis missed by conventional scans, scientists say.
New blood tests for multiple cancers gain political backing
As new technology capable of detecting dozens of early-stage cancer types with a single blood test hits the market, support for its use is building.
Survey shows women are confused about when to start mammograms
A new national survey reveals many women are unsure about when to start mammogram screening for breast cancer and believe they should start later than
Academic burnout pushes Chinese adolescents toward excessive online gaming habits
Chinese researchers report that academic burnout can push adolescents towards excessive online gaming. Using a large-scale cross-sectional survey, the researchers assessed the associations among academic
Multiple myeloma mortality rates decline with advances in targeted therapies
A new research paper was published in Volume 17 of Oncotarget on April 28, 2026, titled “Targeted therapeutics and U.S. population-level mortality trends in multiple
Researchers use light-activated nanozymes to treat aggressive brain tumors
Brain tumors cannot always be successfully treated with conventional therapies. A team from Empa and the hospital network HOCH Health Ostschweiz is therefore developing nanozymes
Cells filter physical forces based on duration to detect disease
Scientists have discovered how cells decide when to respond to physical forces, potentially opening new avenues for tackling diseases such as cancer and fibrosis.
New hybrid molecule uses Trojan horse approach to treat obesity
A team led by metabolism researcher Prof Timo D. Müller at Helmholtz Munich has developed a new approach for treating obesity and type 2 diabetes: