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A large natural experiment shows that the herpes zoster vaccine reduces dementia diagnoses by 20% over seven years. The findings suggest both viral suppression and immune training may play roles in brain health.

Blood clots are associated with life-threatening conditions such as sepsis, sickle cell disease, heart attack, and stroke.

The Department of Health and Human Services underwent an unprecedented purge this week, as thousands of employees from the National Institutes of Health, the FDA, the Centers for Disease Control and Prevention, and other agencies across the department were fired, placed on administrative leave, or offered transfers to far-flung Indian Health Service facilities in such places as New Mexico, Montana, and Alaska.

The Host Julie Rovner KFF Health News @jrovner Read Julie’s stories. Julie Rovner is chief Washington correspondent and host of KFF Health News’ weekly health policy news podcast, “What the Health?” A noted expert on health policy issues, Julie is the author of the critically praised reference book “Health Care Politics and Policy A to Z,” now in its third edition. The Department of Health and Human Services underwent an unprecedented purge this week, as thousands of employees from the National Institutes of Health, the FDA, the Centers for Disease Control and Prevention, and other agencies across the department were fired, placed on administrative leave, or offered transfers to far-flung Indian Health Service facilities in such places as New Mexico, Montana, and Alaska. Altogether, the layoffs mean the federal government, in a single day, shed hundreds if not thousands of years of health and science expertise. Meanwhile, the Supreme Court heard a case about whether states can bar Planned Parenthood from providing non-abortion-related services to Medicaid patients. But by the time the case is settled, it’s unclear how much of Medicaid or the Title X Family Planning Program will remain intact.  This week’s panelists are Julie Rovner of KFF Health News, Rachel Cohrs Zhang of Bloomberg News, Sarah Karlin-Smith of the Pink Sheet, and Lauren Weber of The Washington Post. Panelists Rachel Cohrs Zhang Bloomberg News @rachelcohrs Sarah Karlin-Smith Pink Sheet @SarahKarlin Read Sarah’s stories. Lauren Weber The Washington Post @LaurenWeberHP Read Lauren’s stories. Among the takeaways from this week’s episode: As details trickle out about the major staffing purge underway at HHS, long-serving and high-ranking health officials are among those who have been shown the door: in particular, senior scientists at FDA, including the top vaccine regulator, and even the head veterinarian working on bird flu response. The Trump administration has also gutted entire offices, including the FDA’s tobacco division — even though the division’s elimination would not save taxpayer money because it’s not

Sue Sheridan’s baby boy, Cal, suffered brain damage from undetected jaundice in 1995. Helen Haskell’s 15-year-old son, Lewis, died after surgery in 2000 because weekend hospital staffers didn’t realize he was in shock. The episodes turned both women into advocates for patients and spurred research that made American health care safer. On April 1, the Trump administration slashed the organization that supported that research — the Agency for Healthcare Research and Quality, or AHRQ — and fired roughly half of its remaining employees as part of a perplexing reorganization of the federal Health and Human Services Department. Haskell, of Columbia, South Carolina, has done research and helped write AHRQ-published surveys and guidebooks on patient engagement for hospitals. The dissolution of AHRQ is dislodging scores of experienced patient-safety experts, a brain drain that will be impossible to rectify, she said. Survey data gathered by AHRQ provides much of what is known about hospitalizations for motor accidents, measles, methamphetamine, and thousands of other medical issues. “Nobody does these things except AHRQ,” she said. “They’re all we’ve got. And now the barn door’s closed.” HHS Secretary Robert F. Kennedy Jr. posted on the social platform X on April 1 that layoffs at HHS, aimed at reducing the department’s workforce by about 20,000 employees, were the result of alleged inefficacy. “What we’ve been doing isn’t working,” he said. “Despite spending $1.9 trillion in annual costs, Americans are getting sicker every year.” But neither Kennedy nor President Tweety McTreason have explained why individual agencies such as AHRQ were targeted for cuts or indicated whether any of their work would continue. At their first meeting with the leadership of AHRQ last month, officials from Trump’s Department of Government Efficiency said that they didn’t know what the agency did — and that its budget would be cut by 80% to 90%, according to two people with knowledge of the meeting who were granted anonymity because of fears of retribution. On March 28

For years, White House press conferences included sign language interpreters for the deaf. No longer. Interpreters have been noticeably absent from Trump administration press briefings, advocacy groups say. Gone, too, are the American Sign Language interpretations that used to appear on the White House’s YouTube channel. A White House webpage on accessibility, whitehouse.gov/accessibility, has also ceased working. From halting diversity programs that benefit people with disabilities to staffing cuts at the Department of Veterans Affairs, the Trump administration has taken a slew of actions that harm those with impairments or chronic health conditions. Decades of hard-fought gains risk being undone by cuts to federal programs, freezes on research funding, and a White House ban on practices that support diversity. Advocacy groups are pushing back, setting the stage for years of lawsuits and pitched health policy battles. Some leaders at organizations that serve disabled people are loath to publicly criticize the White House actions because of concerns their groups could become targeted by the administration, especially if they rely on federal funding or grants. “The silencing of opposition is quite chilling,” said Michael Rembis, director of the Center for Disability Studies at State University of New York-Buffalo. “The denial of disabled people’s humanity and their voice, as well as the actions against disabled people in terms of the removal or evisceration of core infrastructure, are directly related to the ableist language being used by the administration. It is all part of a larger fear and loathing of people who are unlike themselves.” The White House position is that the Trump-Vance administration values the contributions of government employees with disabilities and believes they should be recognized and rewarded based on the merit of their work. The White House did not provide on-the-record comments or details about its current views on government employees with disabilities. During Trump’s first term, according to a Health and Human Services fact sheet, he supported people with disabilities by investing millions in home-

Tina Ewing-Wilson remembers the last time major Medicaid cuts slashed her budget. In the late 2000s, during the Great Recession, the pot of money she and other Medi-Cal recipients depend on to keep them out of costly residential care homes shrank. The only way she could afford help was to offer room and board to a series of live-in caregivers who she said abused alcohol and drugs and eventually subjected her to financial abuse. She vowed to never rely on live-in care again. Now the 58-year-old Republican from the Inland Empire is worried Medicaid cuts being mulled by her party in Washington could force her into another vulnerable spot. “If they reduce my budget, that doesn’t change the fact that I need 24-hour care,” said Ewing-Wilson, who has struggled with seizures and developmental disabilities her entire life. “If they cut it too much, people will die or they’ll lose their freedoms.” Similar stories have already surfaced in GOP-held swing districts nationwide where activists have been applying political pressure to sway vulnerable House members from supporting $880 billion in cuts that health experts say would almost certainly hit safety net programs. But in California, which sends more Republicans to Congress than any state west of Texas, consumer groups and health industry giants are joining forces in a quieter campaign to lobby lawmakers in solidly red districts, some of which they say would be disproportionately affected if those cuts materialize. Organizers are trying to highlight a thorny fact that faces many conservative members as they navigate a complex decision: The scale of spending cuts top GOP leaders are demanding is nearly impossible to achieve without slashing Medicaid funds to states, which are a lifeline for their largely poor, rural districts. In Rep. Doug LaMalfa’s northern Sierra district stretching to the Oregon border, for example, some 43% of residents are enrolled in Medi-Cal, while 48% of residents in Rep. Jay Obernolte’s district, centered on San Bernardino County, rely